KMID : 0043319920150030220
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Archives of Pharmacal Research 1992 Volume.15 No. 3 p.220 ~ p.223
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Anticariogenic beta-Carboline Alkaloids from Commelina communis
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Bae KH
Seo WJ/Kwon TH/Baek SH/Lee SW/Jin KD
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Abstract
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The methanolic extract of Commelina communis (aerial part) showed antibacterial activity aganist a cariogenic bacterium, Streptococcus mutans OMZ 176. The active principles were identified to be beta-carboline alkaloids, 1-carbomethoxy-beta-carboline, norharman and harman, which were bactericidal in the minimal inhibitory concentration (MIC) of 100mcg/ml against the strain.
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